疑似自身免疫病因的感音神经性听力损失：三例报告

Sensorineural hearing loss of suspected autoimmune etiology: a report of three cases.

作者信息

Kataoka H, Takeda T, Nakatani H, Saito H

机构信息

Department of Otolaryngology, Shiga University of Medical Science, Otsu, Japan.

出版信息

Auris Nasus Larynx. 1995;22(1):53-8. doi: 10.1016/s0385-8146(12)80183-0.

DOI:10.1016/s0385-8146(12)80183-0

PMID:7677637

Abstract

The present paper reports three cases of sensorineural hearing loss of suspected autoimmune origin. Cases 1 and 2 were bilateral sensorineural hearing loss which responded to steroid therapy. Case 3 was bilateral fluctuant sensorineural hearing loss in conjunction with systemic lupus erythematosus. The pathogenesis of autoimmune sensorineural hearing loss is not yet fully understood. In two patients, hearing levels improved or stabilized following the use of osmotic expanders. The clinical results suggest that endolymphatic hydrops may participate in autoimmune sensorineural hearing loss.

摘要

本文报告了3例疑似自身免疫性起源的感音神经性听力损失病例。病例1和病例2为双侧感音神经性听力损失，对类固醇治疗有反应。病例3为双侧波动性感音神经性听力损失，伴有系统性红斑狼疮。自身免疫性感音神经性听力损失的发病机制尚未完全明确。在2例患者中，使用渗透性扩张剂后听力水平有所改善或稳定。临床结果表明，内淋巴积水可能参与了自身免疫性感音神经性听力损失。