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肝母细胞瘤:一种罕见的儿科肿瘤。

Hepatoblastoma: a rare pediatric neoplasm.

作者信息

Brown B F, Drehner D M, Saldivar V A

机构信息

Department of Pathology, Darnall Army Community Hospital, Ft. Hood, TX 76544.

出版信息

Mil Med. 1993 Jan;158(1):51-5.

PMID:7679785
Abstract

The differential diagnosis of an abdominal mass in an infant or young child includes hepatoblastoma. This rare embryonal neoplasm of the liver is linked to several congenital abnormalities and may be associated with maternal occupational exposure to metal fumes, petroleum products, or paints. Alpha-fetoprotein is a useful tumor marker that may also be elevated with hepatocellular carcinoma. The relatively better prognosis of hepatoblastoma, if completely resected, mandates its differentiation from hepatoma. The fetal subtype of hepatoblastoma seems to represent a "favorable" histology pattern.

摘要

婴幼儿腹部肿块的鉴别诊断包括肝母细胞瘤。这种肝脏罕见的胚胎性肿瘤与多种先天性异常有关,可能与母亲职业性接触金属烟雾、石油产品或油漆有关。甲胎蛋白是一种有用的肿瘤标志物,肝细胞癌时也可能升高。肝母细胞瘤若能完全切除,其预后相对较好,这就要求将其与肝癌区分开来。肝母细胞瘤的胎儿亚型似乎代表一种“预后良好”的组织学模式。

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