Hahn R G
Department of Anaesthesiology, Huddinge University Hospital, Sweden.
Acta Anaesthesiol Scand. 1993 Feb;37(2):166-9. doi: 10.1111/j.1399-6576.1993.tb03694.x.
The purpose of this study was to assess the risk of alcohol-induced hypoglycaemia from the use of irrigating fluids containing ethanol in transurethral surgery. In the first part of the study, seven healthy male volunteers, aged between 26 and 36, received 1000 ml of irrigating fluid by intravenous infusion. The results confirm the existence of an alcohol-induced decrease in blood glucose when ethanol is given together with 1.5% glycine. In the second part of the study, 40 patients, between 56 and 88 years of age, underwent epidural anaesthesia and a transurethral resection of the prostate (TURP) in which the irrigating fluid used contained 1.5% glycine and either 1% or 2% ethanol. The results suggest that the use of ethanol-containing irrigating fluids is often followed by a slight reduction of the blood glucose level, but the magnitude of this change is too small to be of clinical importance.
本研究的目的是评估经尿道手术中使用含乙醇冲洗液导致酒精性低血糖的风险。在研究的第一部分,7名年龄在26至36岁之间的健康男性志愿者通过静脉输注接受了1000毫升冲洗液。结果证实,当乙醇与1.5%甘氨酸一起给予时,存在酒精诱导的血糖降低。在研究的第二部分,40名年龄在56至88岁之间的患者接受了硬膜外麻醉和经尿道前列腺切除术(TURP),术中使用的冲洗液含有1.5%甘氨酸和1%或2%乙醇。结果表明,使用含乙醇冲洗液后,血糖水平通常会略有下降,但这种变化的幅度太小,不具有临床意义。