Taylor S J, Shalloway D
Section of Biochemistry, Molecular and Cell Biology, Cornell University, Ithaca, New York 14853.
Curr Opin Genet Dev. 1993 Feb;3(1):26-34. doi: 10.1016/s0959-437x(05)80337-5.
The activity of the proto-oncogene encoded c-Src product is tightly regulated in vivo. In recent years, a model has emerged of how this regulation is achieved. In particular, protein kinases and phosphatases that are potential regulators of c-Src activity in the cell cycle have been identified and characterized.
原癌基因编码的c-Src产物的活性在体内受到严格调控。近年来,关于这种调控如何实现的模型已经出现。特别是,已经鉴定并表征了细胞周期中c-Src活性的潜在调节因子——蛋白激酶和磷酸酶。