Hall T J, Chambers T J
Research Department, Ciba-Geigy Ltd., Basel, Switzerland.
Inflamm Res. 1996 Jan;45(1):1-9. doi: 10.1007/BF02263497.
In this article we have overviewed recent important advances in understanding the molecular mechanisms involved in osteoclastic bone resorption. Specifically, new findings relating to osteoclast activation and the process of bone resorption are reviewed and a current overall model of how osteoclasts resorb bone is presented. Controversial research topics concerning the regulation of osteoclast activity are also critically discussed.
在本文中，我们综述了在理解破骨细胞骨吸收所涉及的分子机制方面的近期重要进展。具体而言，回顾了与破骨细胞激活及骨吸收过程相关的新发现，并提出了破骨细胞如何吸收骨的当前总体模型。还对有关破骨细胞活性调节的有争议的研究课题进行了批判性讨论。
