Katsuragi M, Yutani C, Imakita M, Ishibashi-Ueda H, Fujita H
Department of Pathology, National Cardiovascular Center, Osaka, Japan.
Heart Vessels. 1993;8(1):42-7.
Many investigators consider viral myocarditis as an important cause of a dilated cardiomyopathy (DCM)-like state. In assessing myocarditis in endomyocardial biopsy samples, two sets of criteria, i.e., the Edwards and the Dallas criteria, are employed. However, no criteria have been established for cell infiltration in autopsy cases, nor have biopsy criteria for myocarditis been applied in autopsy cases. We analyzed the clinicopathologic features and small round cell infiltration in 42 autopsy cases whose clinical diagnoses were DCM, employing both the Edwards and the Dallas criteria. Of the 42 cases, 12 (29%) showed positive results for both sets of criteria. These 12 positive patients were proven to have myocarditis by autopsy and they showed more severe clinical features than 30 cases with negative cell infiltration.
许多研究者认为病毒性心肌炎是扩张型心肌病（DCM）样状态的一个重要病因。在评估心内膜心肌活检样本中的心肌炎时，采用了两套标准，即爱德华兹标准和达拉斯标准。然而，对于尸检病例中的细胞浸润尚未确立标准，心肌炎的活检标准也未应用于尸检病例。我们采用爱德华兹标准和达拉斯标准，分析了42例临床诊断为DCM的尸检病例的临床病理特征和小圆细胞浸润情况。在这42例病例中，12例（29%）两套标准的结果均为阳性。这12例阳性患者经尸检证实患有心肌炎，且他们的临床特征比30例细胞浸润阴性的病例更为严重。
