Fukui A, Maeda M, Tamai S, Inada Y
Department of Orthopaedic Surgery, Nara Medical University, Japan.
Microsurgery. 1993;14(2):114-9. doi: 10.1002/micr.1920140206.
To determine the reason for survival of a pedicled venous flap in which only a draining vein is preserved, it is important to clarify what kind of blood flow is present in the preserved draining vein. Pedicled venous flaps were prepared on the dorsum of the rat and histologically evaluated using horseradish peroxidase (HRP). HRP was applied between the flap and recipient bed in one group. In the other group, HRP was injected into the femoral vein after the flap was turned over (to prevent contact with the recipient bed). The flaps in these HRP-treated groups were compared with untreated control groups. HRP applied between the flap and recipient bed was imbibed into the flap and subsequently transferred into the preserved draining vein. HRP that was injected into the femoral vein was also found in the draining vein of the flap. These results suggest that (1) plasmatic imbibition occurs in pedicled venous flaps; and (2) antegrade and retrograde blood flow are present in the draining vein.
为了确定仅保留引流静脉的带蒂静脉皮瓣存活的原因，明确保留的引流静脉中存在何种血流情况很重要。在大鼠背部制备带蒂静脉皮瓣，并使用辣根过氧化物酶（HRP）进行组织学评估。一组将HRP应用于皮瓣与受区之间。另一组在皮瓣翻转后（以防止与受区接触）将HRP注入股静脉。将这些HRP处理组的皮瓣与未处理的对照组进行比较。应用于皮瓣与受区之间的HRP被皮瓣吸收，随后转移至保留的引流静脉。注入股静脉的HRP也在皮瓣的引流静脉中被发现。这些结果表明：（1）带蒂静脉皮瓣中发生血浆吸收；（2）引流静脉中存在顺行和逆行血流。
