Levkutová M, Bajová V, Hipíková V, Mojzisová J, Harvan M, Hudák P
Univerzita veterinárskeho lekárstva, Kosice.
Vet Med (Praha). 1993 Jan;38(1):31-42.
Immunomodulative effect of insoluble fungous glucan (IFG) was observed on nine accidentally chosen calves, which were in the age from 4.5-5.5 months. The following items were observed: T, B lymphocytes, white blood cell count, index and activity of phagocytosis, induction and determination of interferon from leukocytes. In the experimental group there was a decrease in B-rosseting cells observed. On the 28-th day and on the 42-th day of experiment duration a significant increase in B-rosseting cells in comparison with control group has been observed. Average values were significantly different on the levels P < 0.01 and P < 0.05. Percentages of T-rosseting cells were almost the same during the whole experiment. In the experimental group on the 7-th and on the 14-th day the decrease has been observed. By the Student's t-test a significant difference in favour of group, where IFG was applicated, has been observed. Percentage of white blood cell count was from 47 to 72 in both groups. When phagocytic activity was evaluated, there was the higher percentage of phagocytic cells in the 7th, 14-th, 21-st, 28-th and 42-th day of experiment when compared with the 0-day value. Concerning the phagocyte index a statistical difference was observed, when compared to the initial value in favour of the experimental group. The initial disbalanced values of interferon, which have been observed during the period from the 7-th to the 21-st day, increased on the 28-th and the 42-nd day of experiment which was statistically confirmed on the following levels: P < 0.05 and P < 0.01.
对9头随机挑选的4.5至5.5月龄小牛观察了不溶性真菌葡聚糖（IFG）的免疫调节作用。观察了以下项目：T、B淋巴细胞、白细胞计数、吞噬指数和活性、白细胞干扰素的诱导和测定。实验组观察到B玫瑰花结细胞减少。在实验持续的第28天和第42天，与对照组相比，B玫瑰花结细胞显著增加。平均数值在P<0.01和P<0.05水平上有显著差异。在整个实验过程中，T玫瑰花结细胞的百分比几乎相同。实验组在第7天和第14天观察到减少。通过学生t检验，观察到应用IFG的组有显著差异。两组白细胞计数百分比均在47至72之间。在评估吞噬活性时，与第0天的值相比，在实验的第7天、第14天、第21天、第28天和第42天吞噬细胞的百分比更高。关于吞噬细胞指数，与初始值相比，观察到有利于实验组的统计学差异。在第7天至第21天期间观察到的干扰素初始失衡值，在实验的第28天和第42天增加，在以下水平得到统计学证实：P<0.05和P<0.01。
