Hipíková V, Mojzisová J, Bajová V, Takácová D, Strojný L
Univerzita veterinárskeho lekárstva, Kosice.
Vet Med (Praha). 1993;38(7):385-94.
Some parameters of cell-mediated immunity (phagocytic activity PA and phagocytic index PI, metabolic activity and migration-inhibitive factor MIF of blood leucocytes) were investigated in calves experimentally infected with IBR virus (group II) and in calves premedicated with glucan seven days before infection (group I). A significant increase in the percentage of phagocytizing cells was observed in both groups of animals on days 2-4 of the experiment (P < 0.01) in comparison with the values before infection. If the two groups of animals were confronted with each other, there was a significant difference in the percentage of phagocytizing cells on days 1 and 2 after infection (P < 0.05), with the higher average values in the calves which were only infected. An evaluation of PI showed a statistically significant difference only in the glucan-treated calves on day 7 after its administration (P < 0.05), i.e. on day zero of the experiment. The inhibition of leucocyte migration ability was found on day 1 after infection, and it persisted for four days, without any significant differences between the groups. An evaluation of the metabolic activity of leucocytes (INT-test) showed a decrease in the calves of both groups in comparison with the initial value, without any significant differences when the values were confronted with each other.
对实验感染传染性牛鼻气管炎病毒的犊牛（第二组）以及在感染前七天用葡聚糖进行预处理的犊牛（第一组）的细胞介导免疫的一些参数（吞噬活性PA和吞噬指数PI、血液白细胞的代谢活性和迁移抑制因子MIF）进行了研究。与感染前的值相比，在实验的第2 - 4天，两组动物中吞噬细胞的百分比均显著增加（P < 0.01）。如果将两组动物相互比较，感染后第1天和第2天吞噬细胞的百分比存在显著差异（P < 0.05），仅感染的犊牛平均数值更高。对PI的评估显示，仅在给予葡聚糖后的第7天（即实验的第0天），经葡聚糖处理的犊牛存在统计学显著差异（P < 0.05）。在感染后第1天发现白细胞迁移能力受到抑制，且持续了四天，两组之间无任何显著差异。对白细胞代谢活性（INT试验）的评估显示，与初始值相比，两组犊牛的代谢活性均降低，两组数值相互比较时无任何显著差异。
