de Araújo V C, Biazolla E R, Moraes N P, Furuse T A, Melhado R M
Department of Oral Pathology, School of Dentistry, University of São Paulo, Brazil.
Oral Surg Oral Med Oral Pathol. 1993 May;75(5):622-5. doi: 10.1016/0030-4220(93)90237-x.
A case of basaloid squamous carcinoma that involves the posterior buccal mucosa is described. The major histopathologic feature is a carcinoma with a basaloid pattern in association with squamous differentiation. The basaloid cells exhibit large and vesicular nuclei and eosinophilic clear or vacuolated cytoplasm. Cells are distributed in cords, trabeculae, or lobules that occasionally show glandular arrangement. The majority of the tumor cells are positive for keratin and a large group of cells distributed in glandular arrangement are positive also for vimentin.
本文描述了一例累及颊黏膜后部的基底样鳞状细胞癌。主要组织病理学特征是具有基底样形态并伴有鳞状分化的癌。基底样细胞表现出大的泡状核和嗜酸性透明或空泡状细胞质。细胞呈条索状、小梁状或小叶状分布,偶尔呈腺样排列。大多数肿瘤细胞角蛋白阳性,呈腺样排列的一大群细胞波形蛋白也呈阳性。