技术级六氯环己烷与氧化乐果25%乳油经皮肤给药后对雌性大鼠的相互作用。
Interaction of technical hexachlorocyclohexane and oxydemeton methyl 25 EC to female rats after dermal application.
作者信息
Raizada R B, Srivastava M K, Singh R P, Kaushal R A, Gupta K P, Dikshith T S
机构信息
Industrial Toxicology Research Centre, Lucknow, India.
出版信息
Indian J Exp Biol. 1993 Feb;31(2):142-6.
Technical hexachlorocyclohexane (HCH, 100 mg/kg/day) and oxydemeton methyl 25 EC (125 mg/kg/day) to female rats for 7, 15 and 30 days individually and in combination through skin application caused pathomorphological changes in vital organs and significant enzymatic changes in liver and serum. However changes produced by the two compounds in combination were not suggestive of potentiation effect at the tested dose level in female rats.
将工业级六氯环己烷（HCH，100毫克/千克/天）和氧化乐果25乳油（125毫克/千克/天）分别单独以及联合经皮肤涂抹给予雌性大鼠7天、15天和30天，导致重要器官出现病理形态学变化，以及肝脏和血清中的酶发生显著变化。然而，在测试剂量水平下，这两种化合物联合产生的变化并未表明对雌性大鼠有增效作用。
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