在费城染色体（Ph）阳性慢性粒细胞白血病病程中，出现的第二例Ph阴性细胞8三体病例。
A second case of trisomy 8 in Philadelphia chromosome (Ph)-negative cells during the course of Ph-positive chronic myelocytic leukemia.
作者信息
Bilhou-Nabera C, Marit G, Devianne I, Viard F, Salzes S, Montastruc M, Renoux M, Broustet A, Reiffers J, Bernard P
出版信息
Genes Chromosomes Cancer. 1993 Apr;6(4):255-6. doi: 10.1002/gcc.2870060414.
PMID:7685633
Abstract
A Ph-positive CML patient who had received a peripheral blood stem cell autograft in chronic phase demonstrated a transient regression of the Ph-positive clone with the concurrent appearance of another clone with trisomy 8. This latter clone disappeared when the patient received alpha-interferon.
摘要
一名慢性期接受外周血干细胞自体移植的Ph阳性慢性髓性白血病患者，其Ph阳性克隆短暂消退，同时出现了另一个伴有8号染色体三体的克隆。当患者接受α干扰素治疗时，后一个克隆消失。
Zotero 插件