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分子医学:临床医生入门指南。第一部分。人类基因表达的基本概念。

Molecular medicine: a primer for clinicians. Part I. Essential concepts of human gene expression.

作者信息

Lindahl R

机构信息

Department of Biochemistry and Molecular Biology, USD School of Medicine, Vermillion 57069.

出版信息

S D J Med. 1993 Apr;46(4):115-20.

PMID:7685924
Abstract

Molecular medicine refers to the application of the tools of modern molecular biology to the practice of medicine. The impact of molecular medicine will be increasingly felt by the practicing clinician as increased understanding of disease etiology, significantly improved diagnostic methods and patient care techniques designed to affect a cure rather than treat symptoms. This first paper in an on-going series provides a basic review of human gene expression as a framework for understanding how molecular medicine is irreversibly altering how clinicians will practice medicine. Subsequent papers will detail the application of molecular biology's tools to the practice of medicine.

摘要

分子医学是指将现代分子生物学工具应用于医学实践。随着对疾病病因的认识不断加深、诊断方法显著改进以及旨在实现治愈而非缓解症状的患者护理技术的发展,临床医生将越来越感受到分子医学的影响。本系列连载文章的第一篇对人类基因表达进行了基本综述,以此作为理解分子医学如何不可逆转地改变临床医生行医方式的框架。后续文章将详细阐述分子生物学工具在医学实践中的应用。

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