Roilides E, Pizzo P A
Pediatric Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.
Hematol Oncol Clin North Am. 1993 Aug;7(4):841-64.
The number of immunocompromised hosts has dramatically increased in recent years. The primary reason for this increase has been the intensification of antineoplastic therapy for the treatment of various malignancies and the explosive spread of human immunodeficiency virus infection. Although the treatment and prevention of many infections have been improved with the rational use of antimicrobial agents, ultimate success can be blunted by protracted impairment of essential host defenses or by the virulence of certain organisms.
