Fujii Y, Yoshida H, Sakou T
Department of Orthopedics, Faculty of Medicine, Kagoshima University, Japan.
In Vivo. 1993 Mar-Apr;7(2):143-6.
The expression of tenascin in yellow ligaments of 67 males and 26 females was investigated by immunohistochemistry. Positive tenascin staining was observed in matrices around fibroblasts of entheses, particularly in transitional regions between the cartilage and ligament in yellow ligaments, in 38 (57%) of 67 males and in 13 (50%) of 26 females examined. The incidence of positive tenascin staining was 62.5, 60.0 and 50.0% of yellow ligaments obtained from cervical, thoracic and lumbar spines, respectively. There were no significant differences in sex or regions examined. The incidence of positive tenascin staining in yellow ligaments of patients between the ages of 10-29 years, 30-49 years, 50-69 years, 70-80 years was 29, 55, 69 and 40%, respectively. The incidence of positive tenascin staining in yellow ligaments obtained from patients with ossification in posterior longitudinal ligaments and yellow ligaments and from patients with other diseases such as lumbar disc hernition, cervical spondylosis or spinal tumors was 80.0 and 47.9%, respectively. These results show that the appearance of tenascin in ligaments varies with aging and is frequent in spinal diseases with ossification.
采用免疫组织化学方法研究了67例男性和26例女性黄韧带中腱生蛋白的表达。在67例接受检查的男性中，38例（57%）以及26例女性中13例（50%）的韧带附着点成纤维细胞周围基质中观察到腱生蛋白阳性染色，尤其是在黄韧带软骨与韧带的移行区域。从颈椎、胸椎和腰椎获取的黄韧带中，腱生蛋白阳性染色的发生率分别为62.5%、60.0%和50.0%。性别和检查部位之间无显著差异。10 - 29岁、30 - 49岁、50 - 69岁、70 - 80岁患者黄韧带中腱生蛋白阳性染色的发生率分别为29%、55%、69%和40%。从后纵韧带和黄韧带骨化患者以及腰椎间盘突出症、颈椎病或脊柱肿瘤等其他疾病患者获取的黄韧带中，腱生蛋白阳性染色的发生率分别为80.0%和47.9%。这些结果表明，腱生蛋白在韧带中的出现随年龄变化，并且在伴有骨化的脊柱疾病中较为常见。
