Seraj I M, Chase D R, Chase R L, King A, Jacokes A
Department of Gynecology and Obstetrics, Loma Linda University Medical Center, California 92354.
Gynecol Oncol. 1993 Aug;50(2):254-8. doi: 10.1006/gyno.1993.1203.
A case of malignant teratoma arising within a dysgenetic gonad in a 21-year-old phenotypic female with a 46 XY karyotype is presented. Admixtures of dysgerminoma, yolk sac tumor in close juxtaposition to embryoid bodies and elements of choriocarcinoma were also present. The contralateral gonad was an unidentifiable fibrovascular streak. Neither gonadoblastoma nor coarse calcifications (such as commonly found in gonadoblastoma) could be identified. We believe that the present case arose de novo in a dysgenetic gonad and, uncharacteristically, was not associated with a gonadoblastoma.
本文报告一例21岁表型为女性、核型为46 XY的发育异常性腺内发生的恶性畸胎瘤。同时还存在未成熟畸胎瘤、紧邻胚体的卵黄囊瘤及绒毛膜癌成分。对侧性腺为无法辨认的纤维血管条索。未发现性腺母细胞瘤,也未发现粗大钙化(如性腺母细胞瘤中常见的)。我们认为,本例是在发育异常的性腺中新生的,并且非典型地未与性腺母细胞瘤相关联。