一名XY女性中的五种不同组织学亚型的生殖细胞恶性肿瘤。

Five different histological subtypes of germ cell malignancies in an XY female.

作者信息

Bremer G L, Land J A, Tiebosch A, van der Putten H W

机构信息

Department of Obstetrics and Gynecology, University Hospital, Maastricht, The Netherlands.

出版信息

Gynecol Oncol. 1993 Aug;50(2):247-8. doi: 10.1006/gyno.1993.1201.

DOI:10.1006/gyno.1993.1201

PMID:8397155

Abstract

A case of a 19-year-old female with 46 XY gonadal dysgenesis and five different histological subtypes of germ cell malignancies is described. Both adnexa were removed, preserving the uterus. Pathology revealed gonadoblastoma with dysgerminoma differentiation present in both gonads and in the left gonad mature teratoma, embryonal carcinoma, and endodermal sinus tumor were identified as well. She received no adjuvant treatment and has remained well 30 months after diagnosis.

摘要

本文描述了一例19岁女性，患有46 XY性腺发育不全，且存在五种不同组织学亚型的生殖细胞恶性肿瘤。双侧附件均已切除，保留了子宫。病理检查显示双侧性腺均存在伴有无性细胞瘤分化的性腺母细胞瘤，左侧性腺还发现了成熟畸胎瘤、胚胎性癌和内胚窦瘤。她未接受辅助治疗，诊断后30个月一直状况良好。