胰岛素依赖型糖尿病：一种自身攻击性疾病。
Insulin-dependent diabetes: a disease of autoaggression.
作者信息
Huang S W, Maclaren N K
出版信息
Science. 1976 Apr 2;192(4234):64-6. doi: 10.1126/science.769160.
PMID:769160
Abstract
Lymphocytes from patients with insulin-dependent diabetes demonstrated significant cytoadherence and cytotoxicity against human insulinoma cells in vitro as compared to lymphocytes from normals. Complement was not involved in insulinoma cell destruction. The findings suggest that insulin-dependent diabetes may be a disease of autoaggression.
摘要
与正常人的淋巴细胞相比，胰岛素依赖型糖尿病患者的淋巴细胞在体外对人胰岛素瘤细胞表现出显著的细胞黏附和细胞毒性。补体不参与胰岛素瘤细胞的破坏。这些发现提示胰岛素依赖型糖尿病可能是一种自身攻击性疾病。
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