Sakai K, Tada T, Fukasaku K, Kyoshima K, Kobayashi S
Department of Neurosurgery, Shinshu University School of Medicine, Nagano.
Neurol Med Chir (Tokyo). 1993 Jul;33(7):429-33. doi: 10.2176/nmc.33.429.
Magnetic resonance imaging often demonstrates gadolinium (Gd) enhancement of the dura mater around meningiomas. The Gd-enhanced dura mater was histologically investigated to detect meningioma cells. Gd enhancement of the dura mater occurred in 11 (79%) of the 14 meningiomas studied, and extended as far as 35 mm from the tumor. Histological examination revealed generation of vascular-rich loose connective tissue at the surface of the dura in all five tumors examined. Some clusters of meningothelial cells were distributed in the loose connective tissue in three of the five specimens, and one cluster was obviously neoplastic. These observations suggest that clusters of meningioma cells occur in the Gd-enhanced dura mater around meningiomas.
磁共振成像常显示脑膜瘤周围硬脑膜钆（Gd）强化。对钆强化的硬脑膜进行组织学研究以检测脑膜瘤细胞。在14例研究的脑膜瘤中，11例（79%）出现硬脑膜钆强化，强化范围距肿瘤最远达35毫米。组织学检查显示，在所有5例检查的肿瘤中，硬脑膜表面均有富含血管的疏松结缔组织形成。5个标本中有3个标本的疏松结缔组织中分布有一些脑膜皮细胞簇，其中1个簇明显为肿瘤性。这些观察结果表明，脑膜瘤细胞簇出现在脑膜瘤周围钆强化的硬脑膜中。
