Ivanić D, Maradin M, Granić P, Popović M
Clinical Institute of Laboratory Diagnosis, University Hospital Centre, Zagreb.
Acta Med Croatica. 1993;47(1):23-6.
A study of the fatty acid content was performed by gas chromatography in the sera of 26 healthy children aged 3-13 years and in the sera of 7 children aged up to three years, both from the Zagreb area. The following parameters were calculated for each subject and each fatty acid individually: mmol/l, mol%, g/l, mass% and mean molecular mass. On the basis of the results, the values of the parameters for the whole group of subjects were calculated. The values of these parameters for some characteristic groups of fatty acids (saturated, unsaturated, monounsaturated and long-chain polyunsaturated fatty acids) were also calculated and their interrelationship is presented. The ratio of fatty acids according to age groups (0-1, 1-3 and 3-13 years) is also shown. Fatty acids C 18:2, C 16:0 and C 18:1 with 32.87 mol%, 22.56 mol% and 20.79 mol%, respectively, were most frequently observed in the children's sera, which correlated well with the generally known data. Essential fatty acids were present in the following amounts: C 20:4, 5.49 mol%; C 22:5, 0.26 mol%; and C 22:6, 0.82 mol%. The sera of the children aged up to one year were found to contain significantly higher amounts of short-chain fatty acids and lower amounts of C 18:2 and C 20:4 than the sera from children older than one year.
采用气相色谱法对萨格勒布地区26名3至13岁健康儿童及7名3岁以下儿童的血清进行了脂肪酸含量研究。分别为每个受试者和每种脂肪酸计算了以下参数:毫摩尔/升、摩尔百分比、克/升、质量百分比和平均分子量。根据结果,计算了整个受试者组的参数值。还计算了一些特征性脂肪酸组(饱和脂肪酸、不饱和脂肪酸、单不饱和脂肪酸和长链多不饱和脂肪酸)的这些参数值,并呈现了它们之间的相互关系。还展示了不同年龄组(0至1岁、1至3岁和3至13岁)的脂肪酸比例。脂肪酸C 18:2、C 16:0和C 18:1分别以32.87摩尔%、22.56摩尔%和20.79摩尔%的比例最常出现在儿童血清中,这与普遍已知的数据高度相关。必需脂肪酸的含量如下:C 20:4为5.49摩尔%;C 22:5为0.26摩尔%;C 22:6为0.82摩尔%。结果发现,1岁以下儿童的血清中短链脂肪酸含量明显高于1岁以上儿童的血清,而C 18:2和C 20:4的含量则低于1岁以上儿童。