[Comparison of 7 anti-hepatitis C virus enzyme immunoassays of the 2nd generation in blood donation services].

Seven enzyme-linked immunosorbent assays for the detection of antibodies to hepatitis C virus were compared: three assays with synthetic peptides in the coating showed overproportional higher rates of initial reactive and also the highest rate of so-called false-positive results in comparison with the RIBA assay. One assay with synthetic peptides had also the most false-negative results in comparison with RIBA-reactive results. The best results are found in assays with recombinant proteins, in which proteins derived from the NS-4 region are present.