[辛德毕斯病毒在BHK - 21细胞中的增殖]
[The multiplication of Sindbis virus in BHK-21 cell].
作者信息
Liang F, Xie J, Zhang Q, Ding M, Zhai Z
机构信息
Department of Biology, Peking University, Beijing.
出版信息
Wei Sheng Wu Xue Bao. 1993 Jun;33(3):161-5.
PMID:7694428
Abstract
One step growth curve of Sindbis virus (SbV) in BHK-21 cells showed that a lot of progeny viruses could be observed at 2 hr. after infection. The titer of virus reached the highest about 10(9)TCID50/ml at 6hr. post infection. The viral morphological characters and morphogenetic process in BHK-21 cells were examined by electron microscopic techniques. The dynamics of viral proteins synthesis and the effect on host cell were studied and discussed in this paper.
摘要
辛德毕斯病毒（SbV）在BHK-21细胞中的一步生长曲线表明，感染后2小时可观察到大量子代病毒。感染后6小时病毒滴度达到最高，约为10(9)TCID50/ml。通过电子显微镜技术检测了BHK-21细胞中病毒的形态特征和形态发生过程。本文研究并讨论了病毒蛋白合成的动力学及其对宿主细胞的影响。
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