Polish L B, Tong M J, Co R L, Coleman P J, Alter M J
Hepatitis Branch, Centers for Disease Control and Prevention, Altanta, GA 30333.
Am J Infect Control. 1993 Aug;21(4):196-200. doi: 10.1016/0196-6553(93)90031-x.
To determine the prevalence of and risk factors for antibody to the hepatitis C virus in hospital employees.
Retrospective testing of serum samples obtained from 1677 hospital employees during a prehepatitis B vaccination program in a private teaching community hospital.
Twenty-three employees (1.4%) were found to have antibody to hepatitis C virus. The prevalence of antibody to hepatitis C virus was higher in blacks (3.4%) than in whites (1.1%, p = 0.03) and Hispanics (2.6%, p = 0.88). In a logistic regression model, factors significantly associated with antibody to hepatitis C virus seropositivity included antibody to hepatitis B core antigen (p = 0.002), a history of blood transfusion (p = 0.03), and needlestick injuries (p = 0.04).
Although the prevalence of antibody to hepatitis C virus in health care workers was not high, needlestick injuries were associated with an increased risk for acquiring hepatitis C virus infection.
确定医院员工中丙型肝炎病毒抗体的流行率及危险因素。
对一家私立教学社区医院在乙肝疫苗接种前项目期间从1677名医院员工采集的血清样本进行回顾性检测。
发现23名员工（1.4%）有丙型肝炎病毒抗体。丙型肝炎病毒抗体在黑人中的流行率（3.4%）高于白人（1.1%，p = 0.03）和西班牙裔（2.6%，p = 0.88）。在逻辑回归模型中，与丙型肝炎病毒抗体血清阳性显著相关的因素包括乙肝核心抗原抗体（p = 0.002）、输血史（p = 0.03）和针刺伤（p = 0.04）。
尽管医护人员中丙型肝炎病毒抗体的流行率不高，但针刺伤与感染丙型肝炎病毒的风险增加有关。
