Ceccatelli S, Eriksson M
Department of Histology and Neurobiology, Karolinska Institute, Stockholm, Sweden.
Brain Res. 1993 Oct 15;625(1):177-9. doi: 10.1016/0006-8993(93)90153-e.
Nitric oxide-synthesizing (NOS) enzyme has been identified in several neural populations, including the hypothalamic paraventricular nucleus (PVN). The PVN plays a major role in regulating milk ejection. In the present study, using in situ hybridization, the effect of lactation on NOS mRNA in the PVN was investigated. A significant increase was seen in the PVN of lactating rats, indicating a possible involvement of nitric oxide in the hypothalamic-pituitary regulation of milk ejection.
一氧化氮合成（NOS）酶已在包括下丘脑室旁核（PVN）在内的多个神经群体中被鉴定出来。PVN在调节乳汁排出中起主要作用。在本研究中，使用原位杂交技术，研究了泌乳对PVN中NOS mRNA的影响。在泌乳大鼠的PVN中观察到显著增加，表明一氧化氮可能参与下丘脑 - 垂体对乳汁排出的调节。
