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儿童过敏症状与其父母过敏症状的关联。

Association of allergic symptoms in children with those in their parents.

作者信息

Abdulrazzaq Y M, Bener A, DeBuse P

机构信息

Department of Paediatrics, Faculty of Medicine and Health Sciences, United Arab Emirates University, Al-Ain.

出版信息

Allergy. 1994 Oct;49(9):737-43. doi: 10.1111/j.1398-9995.1994.tb02096.x.

Abstract

This study investigated the association of asthma, allergic rhinitis, and eczema in United Arab Emirates (UAE) schoolchildren with allergic conditions in their parents. A cross-sectional, population-based study among schoolchildren aged 6-14 years was conducted in Al-Ain City, UAE. The field survey was conducted from October 1992 to May 1993. A questionnaire was distributed to 850 UAE government school students from representative, randomly selected schools with a majority of UAE nationals. The student and both or either of the parents were present during the interview. A detailed clinical history of asthma and wheezing in the target children and a history of asthma and allergic rhinitis in their parents and siblings were obtained. It was found that 13.1% of asthmatic children had mothers with asthma (relative risk (RR) = 2.67; 95% confidence intervals (CI) = 1.65-4.35), and 15.2% had fathers who were asthmatic (RR = 2.85; 95% CI = 1.81-4.49). This contrasted with 4.4% of nonasthmatic children who had fathers with asthma, and 4.1% who had mothers with asthma. A similar pattern was seen with symptoms of allergic rhinitis when it was found that 34.3% of children who had asthma had mothers with allergic rhinitis (RR: 2.74; 95% CI: 1.90-3.94). The corresponding figure for fathers was 12.7% (RR: 0.92; 95% CI: 0.5-1.7). The frequency of either parent of the asthmatic children having allergic rhinitis was 28.6%; for both parents, it was 14.5%. It was also found that asthmatic children had 12.5% of their fathers, 32.8% of their mothers, 26.4% of either of their parents, and 33.3% of both their parents suffering from allergic rhinitis.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

本研究调查了阿拉伯联合酋长国(UAE)学童的哮喘、过敏性鼻炎和湿疹与他们父母的过敏状况之间的关联。在阿联酋艾因市对6至14岁的学童进行了一项基于人群的横断面研究。现场调查于1992年10月至1993年5月进行。向来自具有代表性、随机挑选的学校(大多数为阿联酋国民)的850名阿联酋政府学校学生发放了问卷。在访谈期间,学生及其父母双方或一方在场。获取了目标儿童哮喘和喘息的详细临床病史以及他们父母和兄弟姐妹的哮喘和过敏性鼻炎病史。结果发现,13.1%的哮喘儿童的母亲患有哮喘(相对风险(RR)=2.67;95%置信区间(CI)=1.65 - 4.35),15.2%的哮喘儿童的父亲患有哮喘(RR = 2.85;95%CI = 1.81 - 4.49)。相比之下,非哮喘儿童中4.4%的父亲患有哮喘,4.1%的母亲患有哮喘。在过敏性鼻炎症状方面也观察到类似模式,发现34.3%患有哮喘的儿童的母亲患有过敏性鼻炎(RR:2.74;95%CI:1.90 - 3.94)。父亲的相应比例为12.7%(RR:0.92;95%CI:0.5 - 1.7)。哮喘儿童父母一方患有过敏性鼻炎的频率为28.6%;父母双方都患有的频率为14.5%。还发现,哮喘儿童的父亲中有12.5%、母亲中有32.8%、父母一方中有26.4%以及父母双方中有33.3%患有过敏性鼻炎。(摘要截选至250字)

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