Sweeney D J, Wylie E J
Department of Diagnostic Radiology, Royal Perth Hospital, Western Australia.
Australas Radiol. 1995 Feb;39(1):18-23. doi: 10.1111/j.1440-1673.1995.tb00225.x.
The aim of this study is to demonstrate the spectrum of mammographic appearances of mammary duct ectasia that mimic carcinoma in a breast cancer screening programme. Between February 1989 and March 1993, 40,003 women underwent screening mammography as part of the Western Australia Women's Cancer Prevention Unit screening programme. Fine needle aspiration or excisional biopsy was performed on 1437 women, and 12 cases of cytologically or histologically confirmed mammary duct ectasia were detected. A total of 14 mammographic abnormalities from 12 asymptomatic female patients were biopsied, and confirmed to represent mammary duct ectasia. The mammographic spectrum included eight areas of microcalcification (two of which were extensive), three spiculated masses and three lobulated, partially smooth masses. Five of these women showed no other mammographic stigmata of mammary duct ectasia in either breast. Additional features of mammary duct ectasia, including nipple retraction, retro-areolar duct dilatation or macrocalcification were identified in seven women. Mammographic features of mammary duct ectasia are frequently detected in asymptomatic women undergoing screening mammography and cause no diagnostic dilemma. Occasionally mammary duct ectasia will have a mammographic appearance that is indistinguishable from carcinoma, necessitating breast biopsy. In this study 40% of those women with mammary duct ectasia that were submitted for biopsy had no other feature of mammary duct ectasia that could have suggested the pre-operative diagnosis.
本研究的目的是在乳腺癌筛查项目中,展示酷似癌的乳腺导管扩张症的乳腺钼靶表现谱。1989年2月至1993年3月期间,40003名女性作为西澳大利亚妇女癌症预防单位筛查项目的一部分接受了乳腺钼靶筛查。对1437名女性进行了细针穿刺或切除活检,检测出12例经细胞学或组织学确诊的乳腺导管扩张症。对12例无症状女性患者的14处乳腺钼靶异常进行了活检,确诊为乳腺导管扩张症。乳腺钼靶表现谱包括8处微钙化区域(其中2处范围广泛)、3个毛刺状肿块和3个分叶状、部分边界光滑的肿块。其中5名女性双侧乳房均未显示乳腺导管扩张症的其他钼靶特征。在7名女性中发现了乳腺导管扩张症的其他特征,包括乳头凹陷、乳晕后导管扩张或粗大钙化。在接受乳腺钼靶筛查的无症状女性中经常检测到乳腺导管扩张症的钼靶特征,且不会造成诊断难题。偶尔,乳腺导管扩张症的钼靶表现与癌难以区分,需要进行乳腺活检。在本研究中,接受活检的乳腺导管扩张症女性中有40%没有其他可提示术前诊断的乳腺导管扩张症特征。