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Mouse and human chromosomal assignments of mortalin, a novel member of the murine hsp70 family of proteins.

作者信息

Kaul S C, Wadhwa R, Matsuda Y, Hensler P J, Pereira-Smith O M, Komatsu Y, Mitsui Y

机构信息

National Institute of Bioscience and Human Technology, AIST, Ibaraki, Japan.

出版信息

FEBS Lett. 1995 Mar 20;361(2-3):269-72. doi: 10.1016/0014-5793(95)00177-b.

DOI:10.1016/0014-5793(95)00177-b
PMID:7698336
Abstract

Mortalin has been shown to exhibit differential distributions in cells with mortal and immortal phenotypes. In the present study, we report mot-2 cDNA cloning from RS-4 cells--an immortal clone from CD1-ICR mouse embryonic fibroblasts--and the chromosomal assignments of mortalin related genes to mouse chromosomes 18 and X by fluorescence in situ hybridization. Similar analysis assigned the gene to chromosome 5q31.1 in human.

摘要

相似文献

1
Mouse and human chromosomal assignments of mortalin, a novel member of the murine hsp70 family of proteins.
FEBS Lett. 1995 Mar 20;361(2-3):269-72. doi: 10.1016/0014-5793(95)00177-b.
2
Spontaneous immortalization of mouse fibroblasts involves structural changes in senescence inducing protein, mortalin.小鼠成纤维细胞的自发永生化涉及衰老诱导蛋白mortalin的结构变化。
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Localization of the gene encoding the human heat shock cognate protein, HSP73, to chromosome 11.人类热休克同源蛋白HSP73编码基因定位于11号染色体。
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Genetic differences between the pancytosolic and perinuclear forms of murine mortalin.
Exp Cell Res. 1996 Aug 1;226(2):381-6. doi: 10.1006/excr.1996.0239.
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Induction of cellular senescence by transfection of cytosolic mortalin cDNA in NIH 3T3 cells.
J Biol Chem. 1993 Oct 25;268(30):22239-42.
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Differential subcellular distribution of mortalin in mortal and immortal mouse and human fibroblasts.mortalin在永生化和非永生化小鼠及人类成纤维细胞中的亚细胞差异分布
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Identification of genetic events involved in early steps of immortalization of mouse fibroblasts.
Biochim Biophys Acta. 1994 Dec 15;1201(3):389-96. doi: 10.1016/0304-4165(94)90067-1.
8
Genetic mapping of mouse heat shock protein genes Hsc4a to chromosome 11 and Hsc74 to chromosome 18 and two Hsc74 pseudogenes to chromosomes X and 8.
Genomics. 1999 Mar 15;56(3):358-60. doi: 10.1006/geno.1998.5716.
9
On the cytosolic and perinuclear mortalin: an insight by heat shock.
Biochem Biophys Res Commun. 1993 May 28;193(1):348-55. doi: 10.1006/bbrc.1993.1630.
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Chromosomal location of human genes encoding major heat-shock protein HSP70.编码主要热休克蛋白HSP70的人类基因的染色体定位。
Somat Cell Mol Genet. 1987 Mar;13(2):119-30. doi: 10.1007/BF01534692.

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