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Mouse and human chromosomal assignments of mortalin, a novel member of the murine hsp70 family of proteins.

作者信息

Kaul S C, Wadhwa R, Matsuda Y, Hensler P J, Pereira-Smith O M, Komatsu Y, Mitsui Y

机构信息

National Institute of Bioscience and Human Technology, AIST, Ibaraki, Japan.

出版信息

FEBS Lett. 1995 Mar 20;361(2-3):269-72. doi: 10.1016/0014-5793(95)00177-b.

Abstract

Mortalin has been shown to exhibit differential distributions in cells with mortal and immortal phenotypes. In the present study, we report mot-2 cDNA cloning from RS-4 cells--an immortal clone from CD1-ICR mouse embryonic fibroblasts--and the chromosomal assignments of mortalin related genes to mouse chromosomes 18 and X by fluorescence in situ hybridization. Similar analysis assigned the gene to chromosome 5q31.1 in human.

摘要

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