Goni S, Sawhney H, Gopalan S
Department of Obstetrics and Gynecology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Int J Gynaecol Obstet. 1995 Jan;48(1):31-6. doi: 10.1016/0020-7292(94)02249-6.
To compare the efficacy and complications of oxytocin dose increments at 20- and 60-min intervals for induction of labor in women with low parity.
One hundred women of low parity requiring induction of labor were randomly allocated to 20- and 60-min oxytocin dose increments, 50 patients in each group. The basal oxytocin dose was 1 milliunit/min and doubling of the oxytocin dose was done at intervals of 20 and 60 min.
The group with 60-min increments had a decreased incidence of uterine hyperstimulation, cesarean section and operative vaginal delivery. The induction-delivery interval was similar in both groups.
The oxytocin infusion regimen with increments at 60-min intervals is safer than and equally effective as 20-min incremental intervals.
比较间隔20分钟和60分钟增加缩宫素剂量用于低生育力女性引产的疗效及并发症。
100名需要引产的低生育力女性被随机分为间隔20分钟和60分钟增加缩宫素剂量两组，每组50例患者。缩宫素起始剂量为1毫单位/分钟，分别间隔20分钟和60分钟加倍剂量。
间隔60分钟增加剂量组子宫过度刺激、剖宫产及阴道助产的发生率降低。两组引产至分娩的间隔相似。
间隔60分钟增加缩宫素剂量的输注方案比间隔20分钟增加剂量更安全且疗效相当。
