Nakano K, Mabuchi I
Department of Biology, College of Arts and Sciences, University of Tokyo, Japan.
Gene. 1995 Mar 21;155(1):119-22. doi: 10.1016/0378-1119(94)00917-h.
The rho genes encode a group of low-molecular-weight GTP-binding proteins that show about 30% identity in the amino-acid sequence to the ras gene product. Two cDNA clones, both of which are similar to the rho genes, were isolated from a cDNA library of the fission yeast Schizosaccharomyces pombe, using the human rhoA cDNA as a probe. These genes were called rho1+ and rho2+. The encoded Rho1 protein showed 72.7% identity to the budding yeast RHO1 and 66.8% to human RhoA, and the encoded Rho2 protein showed 53.2% identity to the budding yeast RHO2 and RhoA.
rho基因编码一组低分子量GTP结合蛋白，其氨基酸序列与ras基因产物有30%的同源性。以人rhoA cDNA为探针，从裂殖酵母粟酒裂殖酵母的cDNA文库中分离出两个与rho基因相似的cDNA克隆。这些基因被称为rho1 +和rho2 +。编码的Rho1蛋白与芽殖酵母RHO1有72.7%的同源性，与人类RhoA有66.8%的同源性，编码的Rho2蛋白与芽殖酵母RHO2和RhoA有53.2%的同源性。
