Figueroa Damián R, Sánchez Fernández L, Benavides Covarrubias E
Departamento de Infectología e Inmunología, Instituto Nacional de Perinatología, México, D.F.
Ginecol Obstet Mex. 1995 Feb;63:90-5.
Hepatitis B virus (HBV) infections occur worldwide, with the endemicity of infection varying among geographical areas. Infections acquired by perinatal via commonly become persistent and can progress to chronic liver diseases, including cirrhosis and hepatocellular carcinoma. The possibility of vertical transmission of the VHB infection depend of the serological condition of the mother, women with AgsHB positive can infect 10 to 20% of her fetus while women with AgsHB more AgeHB positive can infect 80-90% of her products. Newborns of women with acute or chronic HBV infection must be immunized with vaccine and hepatitis B immune globulin at birth with the objective to reduce the risk of infection.
乙型肝炎病毒（HBV）感染在全球范围内均有发生，不同地理区域的感染流行程度各异。围产期获得的感染通常会持续存在，并可能进展为慢性肝病，包括肝硬化和肝细胞癌。HBV感染垂直传播的可能性取决于母亲的血清学状况，HBsAg阳性的女性可感染其10%至20%的胎儿，而HBsAg和HBeAg均阳性的女性可感染其80%至90%的后代。急性或慢性HBV感染女性的新生儿必须在出生时接种疫苗和乙型肝炎免疫球蛋白，以降低感染风险。
