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经动脉内输注前列腺素E1使继发性雷诺现象缓解:一例报告

Remission of secondary Raynaud phenomenon using intra-arterial prostaglandin E1 infusion. A case report.

作者信息

Seemann J, Scholz J, Sielwicz M

机构信息

Department of Orthopaedic Surgery, Hospital Neukölln, Berlin, Germany.

出版信息

Int Orthop. 1994;18(6):372-4. doi: 10.1007/BF00187085.

DOI:10.1007/BF00187085
PMID:7698870
Abstract

A man, aged 52 years, who had a secondary Raynaud phenomenon affecting the left hand and index finger had been treated unsuccessfully with intravenous prostaglandin E1 and amputation of the finger was proposed. He was given intra-arterial prostaglandin E1 for 10 days and amputation was not necessary. He recovered almost normal function of his hand and the improvement was maintained after 2 months.

摘要

一名52岁男性,患有继发性雷诺现象,累及左手和食指,此前接受静脉注射前列腺素E1治疗但未成功,有人建议切除该手指。他接受了10天的动脉内前列腺素E1治疗,之后无需进行截肢手术。他的手部功能几乎恢复正常,且2个月后仍保持改善状态。

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1
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本文引用的文献

1
Treatment of vasospastic disease with prostaglandin E1.用前列腺素E1治疗血管痉挛性疾病。
Br Med J. 1980 Oct 18;281(6247):1031-4. doi: 10.1136/bmj.281.6247.1031.
2
Prostaglandin E1 infusions for vascular insufficiency in progressive systemic sclerosis.前列腺素E1输注治疗进行性系统性硬化症的血管功能不全
Ann Rheum Dis. 1981 Aug;40(4):350-4. doi: 10.1136/ard.40.4.350.
3
Prostaglandin E1 in severe Raynaud's phenomenon.
Surgery. 1982 Dec;92(6):953-65.
4
Effects of prostaglandin E1 on microvascular haemodynamics in progressive systemic sclerosis.前列腺素E1对进行性系统性硬化症微血管血流动力学的影响。
Br Med J (Clin Res Ed). 1982 Dec 11;285(6356):1688-90. doi: 10.1136/bmj.285.6356.1688.
5
Studies on pharmacokinetics, platelet function and fibrinolytic activity under various prostaglandin E1 infusion regimens.不同前列腺素E1输注方案下的药代动力学、血小板功能及纤溶活性研究。
Prog Clin Biol Res. 1987;242:365-73.
6
The acute phase response in scleroderma. Differing responses to intravenous PGE1.硬皮病中的急性期反应。对静脉注射前列腺素E1的不同反应。
Clin Exp Rheumatol. 1986 Oct-Dec;4(4):341-5.
7
Pathomechanisms of atherosclerosis beneficially affected by prostaglandin E1 (PGE1)--an update.前列腺素E1(PGE1)对动脉粥样硬化病理机制的有益影响——最新进展
Vasa Suppl. 1989;28:6-13.
8
Therapeutic efficacy of intravenously applied prostaglandin E1.静脉注射前列腺素E1的治疗效果。
Vasa Suppl. 1989;28:19-25.