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Inflammation and axonal regeneration.

作者信息

Richardson P M, Lu X

机构信息

Division of Neurosurgery, Montreal General Hospital, Canada.

出版信息

J Neurol. 1994 Dec;242(1 Suppl 1):S57-60. doi: 10.1007/BF00939244.

DOI:10.1007/BF00939244
PMID:7699412
Abstract

Inflammatory cells and their products contribute to neuronal survival and axonal regeneration after injury. Following sciatic nerve transection in rats, macrophages accumulate in the corresponding dorsal root ganglion, potentially supplying neurotrophic support to nerve cell bodies, and enhancing axonal regeneration. Growth factors characterized for their functions in the haematopoietic and immune systems also act on neurons and vice versa, by sharing common subunits among receptors for cytokines and neurotrophic factors.

摘要

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本文引用的文献

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Regulation of Nerve Growth Factor (NGF) Synthesis in the Rat Central Nervous System: Comparison between the Effects of Interleukin-1 and Various Growth Factors in Astrocyte Cultures and in vivo.
分析针对坐骨神经损伤的免疫反应，发现吞噬作用是神经清创的关键机制。
Elife. 2020 Dec 2;9:e60223. doi: 10.7554/eLife.60223.
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Induced Pluripotent Stem Cell Therapies for Cervical Spinal Cord Injury.诱导多能干细胞治疗颈脊髓损伤
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Acetyl salicylic acid locally enhances functional recovery after sciatic nerve transection in rat.乙酰水杨酸可局部促进大鼠坐骨神经横断后的功能恢复。
Neurol Med Chir (Tokyo). 2013;53(12):839-46. doi: 10.2176/nmc.oa2012-0330. Epub 2013 Oct 21.
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Chemokine receptor Ccr2 is critical for monocyte accumulation and survival in West Nile virus encephalitis.趋化因子受体 Ccr2 对于西尼罗河病毒脑炎中单核细胞的积累和存活至关重要。
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Transcriptome analysis of embryonic and adult sensory axons reveals changes in mRNA repertoire localization.胚胎和成年感觉轴突的转录组分析揭示了 mRNA 谱定位的变化。
RNA. 2011 Jan;17(1):85-98. doi: 10.1261/rna.2386111. Epub 2010 Nov 23.
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