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溶解痛风石组织样本中尿酸盐结晶的不是水,而是福尔马林。

Not water, but formalin, dissolves urate crystals in tophaceous tissue samples.

作者信息

Simkin P A, Bassett J E, Lee Q P

机构信息

Department of Medicine, University of Washington, Seattle 98195.

出版信息

J Rheumatol. 1994 Dec;21(12):2320-1.

PMID:7699635
Abstract

OBJECTIVE

To examine the relative solubility of urate crystals in water, formalin, and ethanol.

METHODS

Weighed aliquots of synthetic crystals were incubated in each solvent for 72 h at 4 degrees C and were then examined by polarized microscopy.

RESULTS

urate crystals were insoluble in alcohol, sparingly soluble in water, and markedly soluble in formalin.

CONCLUSION

The marked solubility of urate in formalin is consistent with formation of urate:formaldehyde addition products.

摘要

目的

研究尿酸盐晶体在水、福尔马林和乙醇中的相对溶解度。

方法

将称取的合成晶体等份在每种溶剂中于4℃孵育72小时,然后用偏光显微镜检查。

结果

尿酸盐晶体不溶于酒精,微溶于水,且易溶于福尔马林。

结论

尿酸盐在福尔马林中的显著溶解性与尿酸盐:甲醛加成产物的形成一致。

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