Kakinohana M, Yusa T, Kawabata T
Department of Anesthesiology, University of the Ryukyus, Faculty of Medicine, Okinawa.
Masui. 1995 Jan;44(1):119-23.
The effect of intraoperative gastric juice retention on the incidence of nausea and vomiting during the first 24 h after anesthesia was studied prospectively in 166 patients (ASA PS I-II) for elective surgery, excluding the patients requiring gastric tube (NG tube) postoperatively. The incidences of postoperative nausea and vomiting in the recovery room and during the first 24 h after operation were 5.7 and 10.0% in NG group, in which NG tube was inserted after intubation and taken off after gastric suction at the end of operation; 15.8 and 7.9% in RA group, in which ranitidine 1 mg.kg-1 was premedicated; and 12.1 and 6.9% in NN group, in which NG tube or ranitidine was not used, respectively. There were no statistical differences in the incidence between these three groups and between NG + RA group and NN group. Other factors such as age, duration of anesthesia and operative procedure also did not influence the incidence. The results suggest that the retention of gastric juice during operation has little effect on the incidence of postoperative nausea and vomiting.
前瞻性研究了166例（ASA PS I-II级）择期手术患者术中胃液潴留对麻醉后24小时内恶心呕吐发生率的影响，排除术后需要留置胃管（鼻胃管）的患者。鼻胃管组（插管后插入鼻胃管，手术结束时胃内容物吸出后拔除）在恢复室及术后24小时内恶心呕吐的发生率分别为5.7%和10.0%；雷尼替丁组（术前给予雷尼替丁1mg·kg-1）分别为15.8%和7.9%；非鼻胃管非雷尼替丁组（未使用鼻胃管或雷尼替丁）分别为12.1%和6.9%。这三组之间以及鼻胃管+雷尼替丁组与非鼻胃管非雷尼替丁组之间的发生率无统计学差异。年龄、麻醉时间和手术操作等其他因素也未影响发生率。结果表明，术中胃液潴留对术后恶心呕吐的发生率影响不大。
