Kuno K, Ogawa A, Hayakawa F, Miyajima Y, Takahashi H, Okumura A, Kato T, Itomi K
Department of Pediatrics, Anjo Kosei Hospital.
Jpn J Antibiot. 1995 Jan;48(1):129-32.
Clinical studies on SY5555 dry syrup, a new oral penem antibiotic, were carried out in the field of pediatrics. The following results were obtained. 1. SY5555 was administered to 10 children with various bacterial infections (2 patients with acute tonsillitis, 2 with acute bronchitis, 1 with pharyngitis, 2 with scarlet fever, 1 with pertussis and 2 with urinary tract infections). The overall clinical efficacy rate was 90%. 2. Side effects or abnormal laboratory test values were not observed except for loose stool in 1 and eosinophilia in 1.
新型口服青霉烯类抗生素SY5555干糖浆在儿科领域开展了临床研究。获得了以下结果。1. 对10例患有各种细菌感染的儿童给予SY5555(2例急性扁桃体炎、2例急性支气管炎、1例咽炎、2例猩红热、1例百日咳和2例尿路感染)。总体临床有效率为90%。2. 除1例出现腹泻和1例出现嗜酸性粒细胞增多外,未观察到副作用或实验室检查值异常。