Sekiguchi T, Okamoto T
Department of Pediatrics, Takamatsu Red Cross Hospital.
Jpn J Antibiot. 1995 Feb;48(2):220-8.
SY5555 in dry syrup (powder which is dissolved before use) or tablet form was given orally to 21 children with acute bacterial infections including 4 with acute pharyngitis, 5 with acute tonsillitis, 7 with acute bronchitis, 2 with acute gastroenteritis, 1 each with scarlet fever, acute lymphadenitis and urinary tract infection. Good to excellent clinical responses were obtained in all of the 21 patients and 8 of 11 strains found as causative organisms in these cases were eradicated and 3 strains were decreased. Loose stools were observed in 3 cases and eosinophilia was observed in 1 case. From the above clinical results, it appears that SY5555 is a useful antibiotic for the treatment of pediatric patients with various bacterial infections.
将SY5555制成干糖浆(使用前需溶解的粉末)或片剂形式,口服给予21名患有急性细菌感染的儿童,其中包括4例急性咽炎、5例急性扁桃体炎、7例急性支气管炎、2例急性肠胃炎、1例猩红热、1例急性淋巴结炎和1例尿路感染。21例患者均获得了良好至优秀的临床反应,在这些病例中发现的11株致病菌株中有8株被根除,3株数量减少。3例出现腹泻,1例出现嗜酸性粒细胞增多。从上述临床结果来看,SY5555似乎是治疗患有各种细菌感染的儿科患者的一种有效抗生素。