Ermolenko V M, Lifshits N L, Mikhĭlov A A, Sumarokov A V
Kardiologiia. 1976 May;16(5):39-45.
Basing on the literature data and their own observations of patients with chronic hemodialysis the authors have analysed the pathogenesis, course, hemodynamic shifts and possibilities of purposeful treatment in terminal uremia. Besides two variants of the hypertension course (controlled and noncontrolled), a third type has been revealed--hypertension difficult to control, in the pathogenesis of which, as well as in the noncontrolled variant, an important role is played by the activization of the renin-angiotensin system. Hemodynamic mechanizms of an abrupt change in the arterial pressure (acute hypotension and hypertensive crisis) in the process of hemodialysis are analysed.
基于文献资料以及他们自身对慢性血液透析患者的观察，作者分析了终末期尿毒症的发病机制、病程、血液动力学变化以及针对性治疗的可能性。除了高血压病程的两种类型（可控型和不可控型）之外，还发现了第三种类型——难以控制的高血压，在其发病机制中，与不可控型一样，肾素 - 血管紧张素系统的激活起着重要作用。分析了血液透析过程中动脉压突然变化（急性低血压和高血压危象）的血液动力学机制。
