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[使用直线加速器(LINAC)的立体定向放射外科:模拟与定位]

[Stereotactic radiosurgery using a linear accelerator (LINAC): simulation and positioning].

作者信息

Takayama M, Nakamura M, Ikezaki H, Ikeda I, Kusuda J, Furuya Y, Hara M, Saito I

机构信息

Department of Radiology, Kyorin University School of Medicine.

出版信息

No Shinkei Geka. 1995 Mar;23(3):223-8.

PMID:7700490
Abstract

Stereotactic radiosurgery using a Gamma unit obtains good results for small intracranial diseases, arteriovenous malformation (AVM) and acoustic neurinoma. In stereotactic radiosurgery using a linear accelerator (LINAC), many fundamental problems are to be solved. 1) accuracy of a LINAC, 2) making the collimators for high energy X-ray narrow beams, 3) dosimetry for high energy X-ray narrow beams, 4) irradiation methods for stereotactic radiosurgery, 5) fixation of a patient's head and 6) simulation of a target. The usefulness of our method for simulation of a target and for positioning for radiosurgery was investigated. High energy X-ray narrow beams obtained with the collimators for narrow beams (field sizes: 9mm phi, 18mm phi and 27mm phi) satisfy clinical requirements for stereotactic radiosurgery, as indicated by dose profiles and isodose curves. No dosimetry method for high energy X-ray narrow beams has been established yet. Of the main irradiation methods for stereotactic radiosurgery, the method using multiple non-coplanar converging arcs needs no drastic reconstruction for use with LINAC. A patient's head was completely fixed by the stereotactic frame (Patil stereotaxic system or Leksell micro-stereotactic system). Simulation of a target was performed under CT scan. On CT image, the center of a target was determined and the three-dimensional coodinate on the stereotactic head frame target was settled so that the target would be reached. The three-dimensional coordinate for the target was coincided with the isocenter of a LINA by the laser beams of three-directional pointers. Afterwards, the target position was finely adjusted, by using the target positioner manipulator system.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

使用伽马刀的立体定向放射外科手术对于小型颅内疾病、动静脉畸形(AVM)和听神经瘤能取得良好效果。在使用直线加速器(LINAC)的立体定向放射外科手术中,有许多基本问题有待解决。1)直线加速器的精度;2)制造用于高能X射线窄束的准直器;3)高能X射线窄束的剂量测定;4)立体定向放射外科手术的照射方法;5)患者头部的固定;6)靶点模拟。研究了我们的靶点模拟方法和放射外科手术定位方法的实用性。用窄束准直器(射野尺寸:9mm直径、18mm直径和27mm直径)获得的高能X射线窄束满足立体定向放射外科手术的临床要求,剂量分布和等剂量曲线表明了这一点。目前尚未建立高能X射线窄束的剂量测定方法。在立体定向放射外科手术的主要照射方法中,使用多个非共面汇聚弧的方法在与直线加速器配合使用时无需进行大幅改造。患者头部通过立体定向框架(帕蒂尔立体定向系统或莱克塞尔微立体定向系统)完全固定。在CT扫描下进行靶点模拟。在CT图像上确定靶点中心,并确定立体定向头部框架靶点上的三维坐标,以便能够到达靶点。通过三向指针的激光束使靶点的三维坐标与直线加速器的等中心重合。之后,使用靶点定位器操纵系统对靶点位置进行微调。(摘要截选至250字)

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