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[肝内门体分流]

[Intrahepatic portosystemic shunts].

作者信息

Grosso M, Spalluto F, Veltri A, Bertolino M, Corsico M, Pedrazzini F

机构信息

Istituto di Radiologia, Università di Torino.

出版信息

Minerva Chir. 1994 Oct;49(10 Suppl 1):69-74.

PMID:7700558
Abstract

We want to present our experience performed at the Institute of Radiology of Turin: 98 TIPS in 97 patients (in 1 patient, twice). METHODS. From March 1992, 97 cirrhotic patients (18 Child A, 48 Child B, 31 Child C) underwent the TIPS procedure for portal hypertension. The indications were digestive hemorrhage in 81 patients (20 of which performed in emergency for acute bleeding), intractable ascites in 13 patients and bleeding prevention in 3 patients. RESULTS. Immediate technical success was obtained in 95/98 cases (96.9%). Patients were monitored by US-Doppler at 24 hours, 2 months and every 6 months and by esophagogastroscopy at 2 and 6 months. Major clinical complications included CID (2 cases), hepatic failure (3 cases), renal insufficiency (2 cases), heart failure (1 case), recurrent bleeding (6 cases) and encephalopathy (15 cases). We had 5 early occlusion and 17 late stenosis of the shunt; 21 patients in this group were successfully treated either by PTA or restenting; one patient underwent a surgical shunt. Mortality rate follow-up was 0/17 among Child A patients, 7/48 (14.5%) among Child B patients and 12/29 (41.3%) among Child C patients. CONCLUSIONS. TIPS is a safe and valuable method for the treatment of portal hypertension. Though shunt stenosis may occur with a certain frequency (22/95, 23.1% in our study), a second intervention is usually effective in reducing gastro-oesophageal varices and ascites.

摘要

我们想介绍我们在都灵放射学研究所开展的经验

97例患者接受了98次经颈静脉肝内门体分流术(TIPS)(1例患者接受了两次)。方法。从1992年3月起,97例肝硬化患者(18例Child A级,48例Child B级,31例Child C级)因门静脉高压接受了TIPS手术。适应证为81例患者的消化性出血(其中20例因急性出血在急诊情况下进行),13例患者的顽固性腹水,以及3例患者的出血预防。结果。95/98例(96.9%)手术即刻技术成功。患者在术后24小时、2个月及每6个月接受超声多普勒监测,并在术后2个月和6个月接受食管胃镜检查。主要临床并发症包括肝内门体分流通道感染(CID,2例)、肝衰竭(3例)、肾功能不全(2例)、心力衰竭(1例)、再出血(6例)和肝性脑病(15例)。我们有5例分流道早期闭塞和17例晚期狭窄;该组21例患者通过经皮腔内血管成形术(PTA)或再次支架置入成功治疗;1例患者接受了外科分流术。Child A级患者随访死亡率为0/17,Child B级患者为7/48(14.5%),Child C级患者为12/29(41.3%)。结论。TIPS是治疗门静脉高压的一种安全且有价值的方法。尽管分流道狭窄可能会以一定频率发生(在我们的研究中为22/95,23.1%),但二次干预通常对减少胃食管静脉曲张和腹水有效。

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