Gonet B
Department of Medical Physics, Pomeranian Medical Academy, Szczecin, Poland.
Physiol Chem Phys Med NMR. 1994;26(4):273-86.
Ozone is one of the most potent toxic agents. The noxious effects of its influence on living organisms appear mainly in the lungs and blood. A considerable role in its action is ascribed to free radicals. In this study the ESR method was applied to indirectly demonstrate the free radical effects, as well as the significance of ascorbate in ozonizing the blood. The effects of ozonizing the blood in vitro indicate the existence of a "local" protective mechanism of the blood cells, while in vivo they point out the consumption of ascorbate in "scavenging" of free radicals.
臭氧是最具毒性的物质之一。其对生物体影响的有害作用主要出现在肺部和血液中。自由基在其作用中起着相当重要的作用。在本研究中，采用电子自旋共振（ESR）方法间接证明自由基的作用，以及抗坏血酸在血液臭氧处理中的意义。体外血液臭氧处理的效果表明血细胞存在“局部”保护机制，而在体内则表明抗坏血酸在自由基“清除”过程中的消耗。
