Lenders H, Pentz S, Brunner M, Pirsig W
ENT Department, University of Ulm, Germany.
Rhinology. 1994 Dec;32(4):167-72.
Seventeen patients were operated suffering from unilateral inverted papilloma of the nasal cavities, in one male associated with malignancy. We investigated these patients pre- and post-operatively by clinical examination, video-endoscopy, acoustic rhinometry, and computed tomography (CT). The aim was to find out which technique delivers reliable information about tumour recurrence in follow-up. By these controls three recurrences could be detected in a period of two-years' follow-up. Our results showed that the combination of CT, video-endoscopy and histological examination of biopsies is reliable to detect recurrence of inverted papilloma. To study the possibilities of detecting tumour recurrence by means of acoustic rhinometry, investigations on models of nasal cavities with various shape, size and location of tumour masses were undertaken. A comparison between the results of the model study and the acoustic rhinometric measurements in patients showed that growth of tumour masses can be detected by this method in an early phase under constant conditions such as nasal models. In patients, however, it is not easy to evaluate the absolute size and site of the growing tumour masses, because there are several factors which lead to false-positive interpretations, such as localized inflammations of the mucosa, crusting and nasal secretion and especially the movements of the soft palate. We conclude from our results that acoustic rhinometry does not deliver more information than obtained by video-endoscopy and CT to detect tumour recurrence in the nasal cavity.
17例患有单侧鼻腔内翻性乳头状瘤的患者接受了手术治疗，其中1例男性患者合并恶性肿瘤。我们在术前和术后通过临床检查、视频鼻内镜检查、鼻声反射测量法和计算机断层扫描（CT）对这些患者进行了调查。目的是找出哪种技术能在随访中提供有关肿瘤复发的可靠信息。通过这些检查，在两年的随访期内检测到3例复发。我们的结果表明，CT、视频鼻内镜检查和活检组织学检查相结合对于检测内翻性乳头状瘤的复发是可靠的。为了研究通过鼻声反射测量法检测肿瘤复发的可能性，我们对具有不同形状、大小和肿瘤块位置的鼻腔模型进行了研究。模型研究结果与患者鼻声反射测量结果的比较表明，在诸如鼻腔模型等恒定条件下，该方法可以在早期检测到肿瘤块的生长。然而，在患者中，评估生长中的肿瘤块的绝对大小和位置并不容易，因为有几个因素会导致假阳性解释，如黏膜局部炎症、结痂和鼻分泌物，尤其是软腭的运动。我们从结果中得出结论，在检测鼻腔肿瘤复发方面，鼻声反射测量法提供的信息并不比视频鼻内镜检查和CT更多。
