Lee Ta-Jen, Huang Shiang-Fu, Lee Li-Ang, Huang Chi-Che
Department of Otolaryngology, Chang Gung Memorial Hospital, Taipei, Taiwan.
Laryngoscope. 2004 Jan;114(1):106-12. doi: 10.1097/00005537-200401000-00019.
OBJECTIVES/HYPOTHESIS: Inverted papilloma of the nose and paranasal sinuses is noted for its high rate of recurrence. The feasibility of endoscopic treatment for inverted papilloma has been shown in the literature; however, reports discussing the efficacy of endoscopic surgery for recurrent diseases are rare. The study determined the effectiveness of endoscopic surgery for recurrent inverted papilloma and described when endoscopic medial maxillectomy was indicated.
Retrospective.
Seventeen patients with recurrent inverted papilloma were treated over a 10-year period. Krouse's staging system was used for tumor grading. Because of the extent of the tumor in the majority (70.6%) of the patients, en bloc resection could not be regularly achieved; therefore, sequential segmental endoscopic surgery was the chosen treatment. Some diseases that extensively involved the maxillary sinus were treated by the combination of endoscopic medial maxillectomy (EMM) and sequential segmental surgery (SSES) to extirpate the whole disease.
Efficacy was evaluated strictly by radiographic study. Successful treatment was accomplished in 14 (82.4%) patients. Three (17.6%) patients had residual disease; each required one revision surgery. None of the patients had recurrence at the time of writing. There were no major complications or associated malignancies encountered in the patients.
Endoscopic surgery is an effective treatment for recurrent inverted papilloma. Precise determination of the sites of tumor origin and attachment during the operation is the key to the successful treatment. Recurrent inverted papilloma tends to behave more aggressively and has a higher postoperative recurrence rate than the primary lesion. Stage III disease had a higher recurrence rate (27.3%) than that of other stages (0%).
目的/假设:鼻及鼻窦内翻性乳头状瘤以其高复发率而闻名。文献已表明内镜治疗内翻性乳头状瘤的可行性;然而,讨论内镜手术治疗复发性疾病疗效的报道很少。本研究确定了内镜手术治疗复发性内翻性乳头状瘤的有效性,并描述了何时需要进行内镜下上颌骨内侧切除术。
回顾性研究。
在10年期间对17例复发性内翻性乳头状瘤患者进行了治疗。采用Krouse分期系统对肿瘤进行分级。由于大多数(70.6%)患者的肿瘤范围,无法常规实现整块切除;因此,选择了序贯性节段性内镜手术作为治疗方法。一些广泛累及上颌窦的疾病通过内镜下上颌骨内侧切除术(EMM)和序贯性节段性手术(SSES)联合治疗,以彻底切除整个病变。
通过影像学研究严格评估疗效。14例(82.4%)患者治疗成功。3例(17.6%)患者有残留疾病;每例均需进行一次翻修手术。在撰写本文时,所有患者均无复发。患者未出现重大并发症或相关恶性肿瘤。
内镜手术是治疗复发性内翻性乳头状瘤的有效方法。术中精确确定肿瘤起源和附着部位是成功治疗的关键。复发性内翻性乳头状瘤往往比原发性病变表现得更具侵袭性,术后复发率更高。Ⅲ期疾病的复发率(27.3%)高于其他阶段(0%)。