[Carbamide kinetics in the evaluation of the therapeutic quality of hemodialysis].

A urea kinetic analysis, (the Sargent and Gotch model), was applied to 62 haemodialysis patients. The protein catabolic rate was below 1 g/kg/day in 56.5% of the patients and 66.3% had a KT/V (Clearance x Time/Volume) below 1. The median KT/V was 0.90 and the median normalized protein catabolic rate was 0.95 g/kg/day. KT/V was strongly correlated to protein intake (normalized protein catabolic rate). It is concluded that urea kinetic modelling is a practical tool for assessing the dialysis adequacy and nutritional status of haemodialyzed patients.