Christensen E M, Gjerris A
Psykiatrisk afdeling E, Bispebjerg Hospital, København.
Ugeskr Laeger. 1995 Feb 27;157(9):1185-8.
In 1984 Rosenthal described for the first time the syndrome "Seasonal Affective Disorder", SAD, characterized by annual recurrent depressive episodes in the autumn and winter months possibly followed by mania/hypomania in the summer months. The depressive phases showed atypical symptoms such as hypersomnia, carbohydrate-craving, and weight gain. Melatonin seems to be an indicator of disturbed circadian rhythm rather than the cause of SAD. The importance of other circadian and annual biological rhythm in relation to SAD and other depressive syndromes is quite unknown. SAD differs from classical manic-depressive disorders by frequency, severity, symptomatology, and the typical seasonal variations, and is probably not a subgroup of the classical affective disorders, but an extreme variation of the normal seasonal affective variations seen in the general population. Light therapy can be used successfully in depressive states in SAD.
1984年,罗森塔尔首次描述了“季节性情感障碍”(SAD)综合征,其特征为每年秋冬季节反复出现抑郁发作,夏季可能继以躁狂/轻躁狂发作。抑郁阶段表现出非典型症状,如嗜睡、嗜食碳水化合物和体重增加。褪黑素似乎是昼夜节律紊乱的一个指标,而非SAD的病因。其他昼夜节律和年度生物节律与SAD及其他抑郁综合征的关系尚不清楚。SAD在发作频率、严重程度、症状学及典型的季节性变化方面与经典的躁狂-抑郁性障碍不同,它可能不是经典情感障碍的一个亚组,而是普通人群中正常季节性情感变化的一种极端形式。光疗法可成功用于SAD的抑郁状态。