Méndez Nieto C M, Ramírez Mayans J, Cervantes Bustamente R, Mata Rivera N, Cuevas Schatz F, Martínez C, Gómez Suárez R, Navarrete N
Servicio de Gastroenterología, Instituto nacional de Pediatría, Ciudad de México.
Acta Gastroenterol Latinoam. 1994;24(3):169-74.
We studied 40 children with recurrent abdominal pain during a period of six months (january to june 1993) entered at the gastroenterology service of the Instituto Nacional de Pediatria in México City. In all of then we performed in all of them an upper gastrointestinal endoscopy with 3 biopsies from gastric mucosa (antrum) for histological examination and urease tests. We also did an ELISA test looking for an H. Pylori specific serum IgG response. Our control group were 40 healthy children in whom we did only the ELISA test. We did not find any statistics differences between the histologic findings (gold standard) and the urease and ELISA tests. With IgG antibodies prevalence for H. Pylori in children with recurrent abdominal pain were 57% in contrast with our control group in whom the prevalence was 5%.
我们对40名反复腹痛的儿童进行了为期6个月（1993年1月至6月）的研究，这些儿童均就诊于墨西哥城国家儿科研究所的胃肠病科。我们对所有患儿均进行了上消化道内镜检查，并从胃黏膜（胃窦）取3块组织进行组织学检查和尿素酶检测。我们还进行了酶联免疫吸附测定（ELISA）试验，以检测幽门螺杆菌特异性血清IgG反应。我们的对照组为40名健康儿童，仅对他们进行了ELISA试验。我们未发现组织学检查结果（金标准）与尿素酶检测及ELISA试验之间存在统计学差异。反复腹痛儿童中幽门螺杆菌IgG抗体的患病率为57%，而我们对照组的患病率为5%。
