Cernák A, Krajcírová M, Cierna I, Zaviacic M, Simkovicová M, Elánová E, Bibza J
II. detská klinika DFNsP, Bratislava.
Cesk Pediatr. 1993 Nov;48(11):656-8.
Chronic and recurrent abdominal pain are frequent diagnostic problems in school age and adolescent children. The authors examined the IgG antibodies to Helicobacter pylori using ELISA in a group of 91 children. Positive results were found in 20 children, i.e. 22%. All children positive for Helicobacter pylori antibodies underwent an endoscopic examination with bioptic sampling of the gastric and duodenal mucosa. Bioptic samples were examined histologically and Helicobacter pylori was identified microscopically and using urease tests and cultivation. All 20 children with antibodies to Helicobacter pylori had histological evidence of chronic gastritis in the gastric antrum and infection with Helicobacter pylori was found in 16 cases. Detection of Helicobacter pylori IgG antibodies is useful in the selection of patients for endoscopic examination of the stomach and duodenum. Endoscopy is relevant also where antibodies to Helicobacter pylori are negative and the characteristic picture of chronic disease of the upper gastrointestinal tract is present.
慢性复发性腹痛是学龄期和青少年儿童常见的诊断难题。作者使用酶联免疫吸附测定法（ELISA）检测了91名儿童体内抗幽门螺杆菌的IgG抗体。在20名儿童中发现了阳性结果，即22%。所有幽门螺杆菌抗体呈阳性的儿童都接受了内镜检查，并对胃和十二指肠黏膜进行了活检取样。对活检样本进行了组织学检查，并通过显微镜检查、尿素酶试验和培养来鉴定幽门螺杆菌。所有20名抗幽门螺杆菌抗体阳性的儿童在胃窦部均有慢性胃炎的组织学证据，其中16例发现有幽门螺杆菌感染。检测抗幽门螺杆菌IgG抗体有助于选择进行胃和十二指肠内镜检查的患者。在内镜检查中，即使抗幽门螺杆菌抗体呈阴性，但存在上消化道慢性病的典型症状时，内镜检查也很有必要。
