McNicol A M, Richmond J, Charlton B G
University Department of Pathology, Glasgow Royal Infirmary University, NHS Trust, UK.
Acta Anat (Basel). 1994;151(2):120-3. doi: 10.1159/000147652.
Immunohistochemical detection of the neurone-specific ubiquitin hydrolase protein gene product 9.5 (PGP 9.5) has been applied to the normal adult human adrenal cortex to define overall patterns of innervation. Three distinct types of nerve morphology were noted in the cortex: large nerve trunks traversing the cortex to the medulla, a complex, branching network of slender nerve bundles and individual nerve fibres. These were more abundant in the head and body than in the alae and tail. Varicosities suggested local neurotransmitter release. Nerve fibres were also identified in the muscular wall of the central vein, which are apparently neither noradrenergic nor cholinergic. These data are in support of a direct role for nerves in the control of adrenocortical function and/or vascular responses in man.
免疫组织化学检测神经元特异性泛素水解酶蛋白基因产物9.5（PGP 9.5）已应用于正常成年人类肾上腺皮质，以确定神经支配的总体模式。在皮质中发现了三种不同类型的神经形态：贯穿皮质至髓质的大神经干、纤细神经束和单个神经纤维组成的复杂分支网络。这些在肾上腺的头部和体部比翼部和尾部更为丰富。膨体提示局部神经递质释放。在中央静脉的肌壁中也发现了神经纤维，这些神经纤维显然既不是去甲肾上腺素能的也不是胆碱能的。这些数据支持神经在人类肾上腺皮质功能控制和/或血管反应中起直接作用。
