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用于气管插管神经肌肉阻滞监测的双重爆发刺激

Double burst stimulation for monitoring neuromuscular blockade for tracheal intubation.

作者信息

Jain A K, Sharma P K, Bhattacharya A

机构信息

Department of Anaesthesiology and Critical Care, University College of Medical Sciences, Delhi, India.

出版信息

Anaesthesia. 1995 Jan;50(1):23-5. doi: 10.1111/j.1365-2044.1995.tb04507.x.

DOI:10.1111/j.1365-2044.1995.tb04507.x
PMID:7702138
Abstract

Responses to double burst stimulation were palpated every 15 s after intravenous administration of vecuronium 0.2 mg.kg-1 in 60 adult patients under anaesthesia. Intubating conditions and neuromuscular responses to tracheal intubation were assessed at disappearance of one or both palpable responses to double burst stimulation in groups of 30 patients randomly divided, although in group A patients, tracheal intubation could be performed at disappearance of one palpable response to double burst stimulation; 27 out of 30 patients (90%) had mild to moderate bucking on intubation. In this group, only five patients (16.66%) had good intubating conditions. In group B, where tracheal intubation was attempted at disappearance of both palpable responses, intubating conditions were good in 28 out of 30 patients (93.33%) and there was no response to tracheal intubation in 26 out of 30 patients (86.66%). Palpation of evoked response to double burst stimulation can be used to predict intubating conditions and neuromuscular response to tracheal intubation with nondepolarising muscle relaxants such as vecuronium.

摘要

在60例接受麻醉的成年患者静脉注射0.2mg·kg-1维库溴铵后,每隔15秒触诊一次对双短强直刺激的反应。将30例患者随机分为一组,在双短强直刺激的一个或两个可触知反应消失时,评估气管插管的条件和对气管插管的神经肌肉反应,不过在A组患者中,在双短强直刺激的一个可触知反应消失时即可进行气管插管;30例患者中有27例(90%)在插管时出现轻度至中度呛咳。在该组中,只有5例患者(16.66%)插管条件良好。在B组中,在两个可触知反应均消失时尝试气管插管,30例患者中有28例(93.33%)插管条件良好,30例患者中有26例(86.66%)对气管插管无反应。对双短强直刺激诱发反应的触诊可用于预测使用维库溴铵等非去极化肌松药时的气管插管条件和对气管插管的神经肌肉反应。

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