Boughaleb D, Mansourati J, Genet L, Barra J, Mondine P, Blanc J J
Service de cardiologie, CHU Morvan, Brest.
Arch Mal Coeur Vaiss. 1994 Jul;87(7):925-30.
Between January 1981 and June 1992, 382 patients, operated by the same surgical team, underwent aortic valve replacement for pure severe aortic stenosis. This population was divided into 2 groups according to whether or not surgery was complicated by the development of a conduction defect (atrioventricular and/or intraventricular block), necessitating permanent cardiac pacing. The aim of this study was to analyse not only the incidence and predictive factors but also the long-term prognosis of the paced patients (Group II: 22 patients) in comparison with the control group (Group I: 360 patients). The results showed: the incidence of permanent cardiac pacing after this type of surgery remains low (5.7%); the predictive factors of atrioventricular block requiring permanent pacing were: pre-existing conduction defect (p < 0.02), decreased ejection fraction (p < 0.05), calcification extending to the subaortic interventricular septum (p < 0.0001); the long-term prognosis of the patients was good with 5 and 10 year actuarial survival rates of 95.4% and 68.9% respectively, identical to those of the control group.
1981年1月至1992年6月期间,由同一手术团队进行手术的382例患者因单纯严重主动脉瓣狭窄接受了主动脉瓣置换术。根据手术是否并发传导缺陷(房室和/或室内传导阻滞)而需要永久心脏起搏,将该人群分为两组。本研究的目的不仅是分析发病率和预测因素,而且还要分析接受起搏治疗的患者(第二组:22例患者)与对照组(第一组:360例患者)相比的长期预后。结果显示:此类手术后永久心脏起搏的发生率仍然较低(5.7%);需要永久起搏的房室传导阻滞的预测因素为:既往存在传导缺陷(p<0.02)、射血分数降低(p<0.05)、钙化延伸至主动脉下室间隔(p<0.0001);患者的长期预后良好,5年和10年实际生存率分别为95.4%和68.9%,与对照组相同。