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Synthesis and pharmacological study of some derivatives of pyrazolo[4,3-c]pyrido[3,2-c]-1,2-thiazine-5,5-dioxide, a novel heterocyclic ring system.

作者信息

Malinka W, Sieklucka-Dziuba M, Rajtar-Cynke G, Gasior M, Kleinrok Z

机构信息

Department of Drug Chemistry, Wroclaw University of Medicine, Poland.

出版信息

Farmaco. 1995 Jan;50(1):29-35.

PMID:7702718
Abstract

Starting from pyridothiazines 1 and N-methyl(phenyl)hydrazines isomeric derivatives 2 and 3 of the pyrazolo[4,3-c]pyrido[3,2-e]-1,2-thiazine, a new heterocyclic ring system, have been obtained. The structure of the synthesized compounds was confirmed by spectroscopic and elemental analyses. The results of the preliminary pharmacological study of CNS effects caused by compounds 2 are reported.

摘要

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